Biomimetic high-valent non-heme iron oxidants for the cis-dihydroxylation and epoxidation of olefins

被引：117

作者：

Bautz, Jochen ^{[1
]}

Comba, Peter ^{[1
]}

de laorden, Carlos Lopez ^{[1
]}

Menzel, Matthias ^{[1
]}

Rajaraman, Gopalan ^{[1
]}

机构：

[1] Heidelberg Univ, Inst Anorgan Chem, INF 270, D-69120 Heidelberg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 42期

关键词：

dihydroxylation; epoxidation; iron; oxidation; reaction mechanisms;

D O I：

10.1002/anie.200701681

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pathfinding: The iron(II) complex of the bispidine ligand L1 is oxidized with H2O2 to intermediate-spin [(L 1)FeIVOH)2]2+ (1, see picture) which forms eis diols 2 from olefins, and the high-spin [(L1)Fe IV=O(OH2)]2+ ferryl complex (3) results in epoxidation (4). Product distributions (diol/epoxide) and 18O labeling studies are used to propose a mechanism, which is fully supported by DFT analyses. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：8067 / 8070

页数：4

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