Microfluidic systems for integrated, high-throughput DNA analysis.

被引：31

作者：

Kelly, RT ^{[1
]}

Woolley, AT ^{[1
]}

机构：

[1] Brigham Young Univ, Dept Chem & Biochem, Provo, UT 84602 USA

来源：

ANALYTICAL CHEMISTRY | 2005年 / 77卷 / 05期

关键词：

D O I：

10.1021/ac0533467

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In the decade since the first DNA analyses with microfabricated glass chips were reported, significant advances in sample throughput and integration have poised microfluidics to provide substantial benefit to DNA analysis. Ryan T. Kelly and Adam T. Woolley at Brigham Young University discuss recent developments in systems made with planar microfabrication technology. © 2005 American Chemical Society.

引用

页码：96A / 102A

页数：7

共 43 条

[1] Advanced polymers for DNA separation [J].

Barbier, V ;

Viovy, JL .

CURRENT OPINION IN BIOTECHNOLOGY, 2003, 14 (01) :51-57

[2] Microchip-based purification of DNA from biological samples [J].

Breadmore, MC ;

Wolfe, KA ;

Arcibal, IG ;

Leung, WK ;

Dickson, D ;

Giordano, BC ;

Power, ME ;

Ferrance, JP ;

Feldman, SH ;

Norris, PM ;

Landers, JP .

ANALYTICAL CHEMISTRY, 2003, 75 (08) :1880-1886

[3]

Buchholz BA, 2002, ELECTROPHORESIS, V23, P1398, DOI 10.1002/1522-2683(200205)23:10<1398::AID-ELPS1398>3.0.CO

[4]

2-8

[5] A vision for the future of genomics research [J].

Collins, FS ;

Green, ED ;

Guttmacher, AE ;

Guyer, MS .

NATURE, 2003, 422 (6934) :835-847

[6] HIGH-SPEED SEPARATION OF ANTISENSE OLIGONUCLEOTIDES ON A MICROMACHINED CAPILLARY ELECTROPHORESIS DEVICE [J].

EFFENHAUSER, CS ;

PAULUS, A ;

MANZ, A ;

WIDMER, HM .

ANALYTICAL CHEMISTRY, 1994, 66 (18) :2949-2953

[7] Microfabricated 384-lane capillary array electrophoresis bioanalyzer for ultrahigh-throughput genetic analysis [J].

Emrich, CA ;

Tian, HJ ;

Medintz, IL ;

Mathies, RA .

ANALYTICAL CHEMISTRY, 2002, 74 (19) :5076-5083

[8] Developments toward a complete micro-total analysis system for Duchenne muscular dystrophy diagnosis [J].

Ferrance, JP ;

Wu, QR ;

Giordano, B ;

Hernandez, C ;

Kwok, Y ;

Snow, K ;

Thibodeau, S ;

Landers, JP .

ANALYTICA CHIMICA ACTA, 2003, 500 (1-2) :223-236

[9] Polymerase chain reaction in polymeric microchips:: DNA amplification in less than 240 seconds [J].

Giordano, BC ;

Ferrance, J ;

Swedberg, S ;

Hühmer, AFR ;

Landers, JP .

ANALYTICAL BIOCHEMISTRY, 2001, 291 (01) :124-132

[10] Soup-to-nuts DNA analysis [J].

Henry, C .

CHEMICAL & ENGINEERING NEWS, 2004, 82 (14) :13-13

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