Age, exercise, and the outcome of sepsis

被引:9
作者
Banerjee, Debasree [1 ,2 ]
Opal, Steven M. [1 ,2 ]
机构
[1] Brown Univ, Warren Alpert Med Sch, Dept Med, 593 Eddy St, Providence, RI 02903 USA
[2] Lifespan Hosp Syst, Providence, RI 02903 USA
来源
CRITICAL CARE | 2017年 / 21卷
关键词
Sepsis; Septic shock; Aging and immunity; Immunosenescence; Exercise and infections; Sepsis in the elderly; IMPACT;
D O I
10.1186/s13054-017-1840-9
中图分类号
R4 [临床医学];
学科分类号
100218 [急诊医学];
摘要
We report on the increasingly important need to diagnose and care for the elderly with sepsis as a distinct patient population. We share an overview of age-related changes in sepsis physiology and the potential role of exercise.
引用
收藏
页数:3
相关论文
共 14 条
[1]
Effect of exercise training on chronic inflammation [J].
Beavers, Kristen M. ;
Brinkley, Tina E. ;
Nicklas, Barbara J. .
CLINICA CHIMICA ACTA, 2010, 411 (11-12) :785-793
[2]
Challenges with Diagnosing and Managing Sepsis in Older Adults [J].
Clifford, Kalin M. ;
Dy-Boarman, Eliza A. ;
Haase, Krystal K. ;
Maxvill, Kristen ;
Pass, Steven E. ;
Alvarez, Carlos A. .
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2016, 14 (02) :231-241
[3]
Impact of physical activity on inflammation: effects on cardiovascular disease risk and other inflammatory conditions [J].
Ertek, Sibel ;
Cicero, Arrigo .
ARCHIVES OF MEDICAL SCIENCE, 2012, 8 (05) :794-804
[4]
Impact of older age and nursing home residence on clinical outcomes of US emergency department visits for severe sepsis [J].
Ginde, Adit A. ;
Moss, Marc ;
Shapiro, Nathan I. ;
Schwartz, Robert S. .
JOURNAL OF CRITICAL CARE, 2013, 28 (05) :606-611
[5]
Benefits of Regular Exercise on Inflammatory and Cardiovascular Risk Markers in Normal Weight, Overweight and Obese Adults [J].
Gondim, Olivia Santos ;
Nunes de Camargo, Vinicius Tadeu ;
Gutierrez, Fernanda Almeida ;
de Oliveira Martins, Patricia Fatima ;
Pereira Passos, Maria Elizabeth ;
Momesso, Cesar Miguel ;
Santos, Vinicius Coneglian ;
Gorjao, Renata ;
Pithon-Curi, Tania Cristina ;
Cury-Boaventura, Maria Fernanda .
PLOS ONE, 2015, 10 (10)
[6]
The aging of the immune system [J].
Grubeck-Loebenstein, B ;
Wick, G .
ADVANCES IN IMMUNOLOGY, VOL 80, 2002, 80 :243-284
[7]
Reduction of Immunocompetent T Cells Followed by Prolonged Lymphopenia in Severe Sepsis in the Elderly [J].
Inoue, Shigeaki ;
Suzuki-Utsunomiya, Kyoko ;
Okada, Yoshinori ;
Iida, Yumi ;
Taira, Takayuki ;
Miura, Naoya ;
Tsuji, Tomoatsu ;
Yamagiwa, Takeshi ;
Morita, Seiji ;
Chiba, Tomoki ;
Sato, Takehito ;
Inokuchi, Sadaki .
CRITICAL CARE MEDICINE, 2013, 41 (03) :810-819
[8]
The effect of aging on circulating levels of proinflammatory cytokines during septic shock [J].
Marik, PE ;
Zaloga, GP .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2001, 49 (01) :5-9
[9]
Animal Models of Aging Research: Implications for Human Aging and Age-Related Diseases [J].
Mitchell, Sarah J. ;
Scheibye-Knudsen, Morten ;
Longo, Dan L. ;
de Cabo, Rafael .
ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 3, 2015, 3 :283-303
[10]
The immunopathogenesis of sepsis in elderly patients [J].
Opal, SM ;
Girard, TD ;
Ely, EW .
CLINICAL INFECTIOUS DISEASES, 2005, 41 :S504-S512