Microarrays in primary breast cancer - lessons from chemotherapy studies

被引：31

作者：

Lonning, PE ^{[1
]}

Sorlie, T

Perou, CM

Brown, PO

Botstein, D

Borresen-Dale, AL

机构：

[1] Haukeland Hosp, Dept Med, Sect Oncol, Bergen, Norway

[2] Norwegian Radium Hosp, Dept Genet, Oslo, Norway

[3] Stanford Univ, Sch Med, Dept Genet, San Francisco, CA USA

[4] Stanford Univ, Sch Med, Dept Biochem, San Francisco, CA USA

[5] Stanford Univ, Sch Med, Howard Hughes Med Inst, San Francisco, CA USA

来源：

关键词：

D O I：

10.1677/erc.0.0080259

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Current development in molecular techniques has extended the opportunities to explore genetic alterations in malignant tissue. There is a need to improve prognostication and, in particular, to understand the mechanisms of treatment resistance in different tumours. Gene analyses by microarrays allow concomitant analyses of several genes in concert, providing new opportunities for tumour classification and understanding of key biological disturbances. This paper outlines our continuing studies exploring prognostic and, we hope, predictive factors in breast cancer therapy.

引用

页码：259 / 263

页数：5

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