The miaA mutator phenotype of Escherichia coli K-12 requires recombination functions

被引:19
作者
Zhao, JY [1 ]
Leung, HCE [1 ]
Winkler, ME [1 ]
机构
[1] Univ Texas, Sch Med, Dept Microbiol & Mol Genet, Houston, TX 77030 USA
关键词
D O I
10.1128/JB.183.5.1796-1800.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
miaA mutants, which contain A-37 instead of the ms(2)i(6)A-37 hypermodification in their tRNA, show a moderate mutator phenotype leading to increased GC->TA transversion. We show that the miaA. mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those required for translation stress-induced mutagenesis.
引用
收藏
页码:1796 / 1800
页数:5
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