Visualizing profile-profile alignment:: pairwise HMM logos

被引：32

作者：

Schuster-Böckler, B ^{[1
]}

Bateman, A ^{[1
]}

机构：

[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

来源：

BIOINFORMATICS | 2005年 / 21卷 / 12期

基金：

英国惠康基金;

关键词：

D O I：

10.1093/bioinformatics/bti434

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The availability of advanced profile-profile comparison tools, such as PRC or HHsearch demands sophisticated visualization tools not presently available. We introduce an approach built upon the concept of HMM logos. The method illustrates the similarities of pairs of protein family profiles in an intuitive way. Two HMM logos, one for each profile, are drawn one upon the other. The aligned states are then highlighted and connected.

引用

页码：2912 / 2913

页数：2

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