Asymmetric reactions of chiral imide enolates with alpha-keto esters

被引：30

作者：

Jacobson, IC

Reddy, GP

机构：

[1] Dept. of Chem. and Physical Sciences, DuPont Merck Pharmaceutical Company, Experimental Station, Wilmington, DE 19880-0500

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 46期

关键词：

D O I：

10.1016/0040-4039(96)01843-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for the synthesis of a variety of 2-hydroxy-2,3-trisubstituted succinates (I) is presented. The synthesis is achieved by the asymmetric reactions of lithium, boron or titanium enolates of Evans' chiral imides with alpha-keto esters. Copyright (C) 1996 The DuPont Merck Pharmaceutical Company, Published by Elsevier Science Ltd

引用

页码：8263 / 8266

页数：4

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