Ultrahigh density microarrays of solid samples

被引：31

作者：

LeBaron, MJ ^{[1
]}

Crismon, HR ^{[1
]}

Utama, FE ^{[1
]}

Neilson, LM ^{[1
]}

Sultan, AS ^{[1
]}

Johnson, KJ ^{[1
]}

Andersson, EC ^{[1
]}

Rui, H ^{[1
]}

机构：

[1] Georgetown Univ, Med Ctr, Lombardi Comprehen Canc Ctr, Dept Oncol, Washington, DC 20057 USA

来源：

NATURE METHODS | 2005年 / 2卷 / 07期

关键词：

D O I：

10.1038/NMETH772

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a sectioning and bonding technology to make ultrahigh density microarrays of solid samples, cutting edge matrix assembly (CEMA). Maximized array density is achieved by a scaffold-free, self-supporting construction with rectangular array features that are incrementally scalable. This platform technology facilitates arrays of > 10,000 tissue features on a standard glass slide, inclusion of unique sample identifiers for improved manual or automated tracking, and oriented arraying of stratified or polarized samples.

引用

页码：511 / 513

页数：3

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