Key concepts in immunology

被引：107

作者：

Moser, Muriel ^{[1
]}

Leo, Oberdan ^{[1
]}

机构：

[1] Univ Libre Bruxelles, Physiol Anim Lab, B-6041 Gosselies, Belgium

来源：

VACCINE | 2010年 / 28卷

关键词：

Immunology; Innate immunity; Adaptive immunity; REGULATORY T-CELLS; CXC CHEMOKINE RECEPTOR-5; TUMOR-NECROSIS-FACTOR; DENDRITIC CELLS; IMMUNE-RESPONSE; SOLUBLE-ANTIGEN; ACTIVATION; HOST; DISTINCT; MEMORY;

D O I：

10.1016/j.vaccine.2010.07.022

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Vertebrates have developed systems of immune defence enabling them to cope with the constant threat posed by environmental pathogens. The mammalian immune system represents a multilayered defence system comprising both innate and adaptive immune responses, characterized by the increasing complexity of their antigen-recognition systems The discovery of the intimate relationship between innate and adaptive responses has paved the way to a novel understanding of the basic mechanisms governing the regulation of an immune response The purpose of the present review is to briefly describe the basic immunological concepts that constitute the founding principles of modern vaccinology in humans (c) 2010 Elsevier Ltd All rights reserved

引用

页码：C2 / C13

页数：12

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