Is high cerebral perfusion pressure and cerebral flow predictive of impending seizures in preeclampsia? A case report

Transcranial Doppler ultrasound was used to demonstrate elevated estimated cerebral perfusion pressure (CPP) and cerebral flow index (CFI) in a preeclamptic patient. She subsequently developed eclampsia. After magnesium sulfate therapy her CPP and CFI were within the normal range and she did not experience further seizures. This finding suggests that cerebral overperfusion may be at least one of the etiologies involved in the pathogenesis of eclampsia.