Imaging of essential and toxic elements in biological tissues by LA-ICP-MS

被引：45

作者：

Becker, J. Sabine ^{[1
]}

Zoriy, Miroslav ^{[1
]}

Wu, Bei ^{[1
,4
]}

Matusch, Andreas ^{[2
]}

Becker, J. Susanne ^{[3
]}

机构：

[1] Res Ctr Julich, Cent Div Analyt Chem, D-52425 Julich, Germany

[2] Univ Marburg, Dept Neurol, D-35033 Marburg, Germany

[3] CNRS UMR 5034, Grp Bioinorgan Analyt Chem, F-64053 Pau, France

[4] Zhejiang Univ, Inst Environm Sci & Technol, Hangzhou 310029, Zhejiang, Peoples R China

来源：

JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY | 2008年 / 23卷 / 09期

关键词：

D O I：

10.1039/b805228j

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) using double-focusing sector field (LA-ICP-SFMS) or quadrupole-based mass spectrometers (LA-ICP-QMS) was employed as powerful imaging (mapping) techniques to produce images of detailed regionally specific element distributions in thin tissue sections of different sizes such as control rat brain tissues or tumor regions to study tumor growing. LA-ICP-QMS was employed to investigate the uptake and the transport of nutrient elements in plant tissues or imaging of metals in proteins separated by native 2D BN-PAGE.

引用

页码：1275 / 1280

页数：6

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