Endocytosis of neurotransmitter receptors: location matters

被引：6

作者：

Puthenveedu, Manojkumar A.

Yudowski, Guillermo A.

von Zastrow, Mark ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Psychiat, San Francisco, CA 94158 USA

[2] Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94158 USA

来源：

CELL | 2007年 / 130卷 / 06期

关键词：

D O I：

10.1016/j.cell.2007.09.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Endocytosis of excitatory glutamate receptors from the postsynaptic plasma membrane plays a fundamental role in synaptic function and plasticity. In a recent study published in Neuron, Lu et al. ( 2007) describe protein interactions that link zones of receptor endocytosis directly to the postsynaptic scaffold and propose that local trafficking of receptors facilitated by these endocytic zones is required to maintain synaptic responsiveness.

引用

收藏

页码：988 / 989

页数：3

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