Long-lived plasma cells: a mechanism for maintaining persistent antibody production

被引：236

作者：

Slifka, MK

Ahmed, R

机构：

[1] Scripps Res Inst, Dept Neuropharmacol, La Jolla, CA 92122 USA

[2] Emory Univ, Sch Med, Emory Vaccine Ctr, Atlanta, GA 30322 USA

[3] Emory Univ, Sch Med, Dept Microbiol & Immunol, Atlanta, GA 30322 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(98)80162-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

引用

页码：252 / 258

页数：7

共 40 条

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