The CTD code

被引:262
作者
Buratowski, S [1 ]
机构
[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
关键词
D O I
10.1038/nsb0903-679
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
How does the C-terminal domain (CTD) of RNA polymerase II interact specifically with multiple targets? A recent paper describing the structure of this domain with a mRNA capping enzyme guanylyltransferase suggests that the CTD is a contortionist that, upon post-translational modification, adopts different configurations specifically recognized by its partners.
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页码:679 / 680
页数:3
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