Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy

被引：71

作者：

Ito, R

Melhem, ER

Mori, S

Eichler, FS

Raymond, GV

Moser, HW

机构：

[1] Johns Hopkins Univ, Dept Pediat, Baltimore, MD 21218 USA

[2] Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21218 USA

[3] Johns Hopkins Univ, Kennedy Krieger Inst, Neurogenet Div, Baltimore, MD 21218 USA

[4] Johns Hopkins Hosp, Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

[5] Shiga Univ Med Sci, Dept Radiol, Otsu, Shiga 52021, Japan

来源：

NEUROLOGY | 2001年 / 56卷 / 04期

关键词：

D O I：

10.1212/WNL.56.4.544

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Brain diffusion tensor MRI of 11 boys with X-linked adrenoleukodystrophy was performed. The authors determined quantitative isotropic apparent diffusion coefficient (ADC(i)) and fractional anisotropy (FA) values in the white matter. ADC(i) and FA values in the affected white matter were significantly different from those in normal-appearing white matter. Zonal ADC(i) and FA gradations, which might originate from well-established histopathologic zonal changes, existed within affected white matter.

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收藏

页码：544 / 547

页数：4

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