Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm

被引:47
作者
Cheng, Xiao-Wen [1 ]
Lu, Juan [2 ,3 ]
Wu, Chun-Li [1 ]
Yi, Li-Na [3 ,4 ]
Xie, Xu [1 ]
Shi, Xiang-Dong [4 ]
Fang, Shi-Song [1 ]
Zan, Hong [6 ]
Kung, Hsiang-fu [3 ,5 ]
He, Ming-Liang [3 ,5 ]
机构
[1] Shenzhen Ctr Dis Control & Prevent, Shenzhen, Peoples R China
[2] So Med Univ, Nanfang Hosp, Dept Otolaryngol Head & Neck Surg, Guangzhou, Guangdong, Peoples R China
[3] Chinese Univ Hong Kong, Stanley Ho Ctr Emerging Infect Dis, Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China
[4] Futian Ctr Dis Control & Prevent, Shenzhen, Peoples R China
[5] Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Hong Kong, Hong Kong, Peoples R China
[6] Univ Calif Irvine, Inst Immunol, Irvine, CA USA
关键词
Influenza A; H1N1; Cytokine storm; H1N1;
D O I
10.1016/j.resp.2010.11.004
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
China had taken strict measures for pandemic 2009 H1N1 infection with enhanced surveillance and hospital isolation since April 2009. In Shenzhen, over 1200 confirmed cases of H1N1 infection were identified. Three young patients died of severe pneumonia. Among them, two boys developed neurological complications. Cytokine storm seemed an important cause. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:185 / 187
页数:3
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