Effect of direct thrombin inhibition with Bivalirudin (Hirulog) on restenosis after coronary angioplasty

被引：22

作者：

Burchenal, JEB

Marks, DS

Mann, JT

Schweiger, MJ

Rothman, MT

Ganz, P

Adelman, B

Bittl, JA

机构：

[1] Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA

[2] Wake Heart Associates, Dept Med, Raleigh, NC USA

[3] Baystate Med Ctr, Dept Med, Springfield, MA 01199 USA

[4] London Chest Hosp, Dept Med, London E2 9JX, England

[5] Biogen Inc, Dept Med, Cambridge, MA 02142 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 82卷 / 04期

关键词：

D O I：

10.1016/S0002-9149(98)00371-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The direct antithrombin, bivalirudin, did not reduce angiographic restenosis measured either as the dichotomous restenosis rate of 62% for bivalirudin and 58% for heparin (p = 0.70), or as the late loss in lumen diameter of 0.44 +/- 0.47 mm for bivalirudin and 0.39 +/- 0.53 mm for heparin (p = 0.62). Direct thrombin inhibition with bivalirudin neither reduces angiographic restenosis nor alters the impact of several established risk factors for restenosis.

引用

页码：511 / +

页数：6

共 19 条

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