Apoptotic PS to phagocyte TIM-4: Eat me

被引：35

作者：

Savill, John ^{[1
]}

Gregory, Chris ^{[1
]}

机构：

[1] Univ Edinburgh, Queens Med Res Inst, MRC, Ctr Inflammat Res, Edinburgh EH16 4TJ, Midlothian, Scotland

来源：

IMMUNITY | 2007年 / 27卷 / 06期

关键词：

D O I：

10.1016/j.immuni.2007.12.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Although cells dying by apoptosis expose the classical "eat me" signal phosphatidylserine (PS), a phagocytic transmembrane receptor for PS has proved elusive. Now cell and structural studies (Kobayashi et al. [2007] and Santiago et al. [2007] in this issue of Immunity) implicate the type I molecule TIM-4.

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页码：830 / 832

页数：3

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