System identification of atrial activation during chronic atrial fibrillation in man

被引：4

作者：

Johansson, R ^{[1
]}

Holm, M

Olsson, SB

Brandt, J

机构：

[1] Lund Inst Technol, Dept Automat Control, S-22100 Lund, Sweden

[2] Univ Lund Hosp, Dept Cardiol, S-22185 Lund, Sweden

[3] Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden

来源：

IEEE TRANSACTIONS ON AUTOMATIC CONTROL | 1998年 / 43卷 / 06期

关键词：

atrial fibrillation; electrogram; impulse response; prediction; state-space realization; system identification;

D O I：

10.1109/9.679019

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

The spatial and temporal organization of excitation during atrial fibrillation is still a question of debate. To further clarify the mechanisms maintaining chronic atrial fibrillation (CAF), a method for system identification of activation patterns of the atria during sinus rhythm (SR), during artificial atrial pacing, and during atrial fibrillation was developed. Data were obtained as repeated recordings of 8 s in duration, each of 56 atrial bipolar electrograms, simultaneously acquired during open-heart surgery at multiple sites in the right atrial-free wall in 12 patients with stable SR and during artificial pacing and 16 patients with CAF, Realization theory (Ho-Kalman and Juang-Pappa algorithms) was applied to fit the multivariate electrograms corresponding to individual beats during SR and type-I activations during AF, respectively. It was possible to reproduce the multivariate electrograms corresponding to individual beats, including their waveform patterns during SR as well as during type-I atrial fibrillation activation-in all cases and for all subjects tested with good accuracy. It was concluded that the local electrogram is a predictable signal during SR, artificial pacing, as well as during type-I atrial activation, and the proposed method may be used for further investigations concerning the deterministic and predictive nature of atrial activation during atrial fibrillation.

引用

页码：790 / 799

页数：10

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