Two year review of intestinal intussusception in six large public hospitals of Santiago, Chile

被引:50
作者
O'Ryan, M
Lucero, Y
Peña, A
Valenzuela, MT
机构
[1] Univ Chile, ICBM, Fac Med, Microbiol Program, Santiago 7, Chile
[2] Univ Chile, Fac Med, Dept Epidemiol, Santiago 7, Chile
[3] Hosp Dr Sotero del Rio, Santiago 7, Chile
关键词
intussusception; rotavirus; vaccine;
D O I
10.1097/01.inf.0000078374.82903.e8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. A need for updated information on different aspects of idiopathic intussusception resurged after the Rotashield experience. Variability of incidence rates worldwide and the possibility of a more severe outcome among infants that have intussusception at a younger age are two issues that remain unclear. We aimed to provide updated information on clinical aspects of intussusception in a large population of Chilean children <2 years of age, including a best estimate of incidence rate and a comparative analysis of the clinical evolution for children younger and older than 6 months of age. Methods. Several sources of information were used to recollect all intussusception cases 0 to 24 months of age treated in six public pediatric hospitals of the Metropolitan area during years 2000 and 2001 and to obtain updated estimates of the population covered by these hospitals. A thorough chart review of intussusception. cases was performed using a standardized case report form. Results. A total of 50 and 45 intussusception. cases were detected for 2000 and 2001, respectively, and estimated intussusception rates for children 0 to 24 months and for the subgroup <12 months of age were 35 and 32 per 100 000, and 55 and 47 per 100000. The monthly distribution of intussusception cases differed for both years without an identifiable reason, and no association between intussusception and rotavirus infection was observed. No intussusception-associated death was recorded. Overall complications occurred in 21% of children, and infants younger than 6 months of age did not have more complications or a more prolonged hospital stay than older children. Conclusions. Idiopathic intussusception is not uncommon among Chilean infants with incidence rates similar to those reported in the United States. There was no clear association with preexisting rotavirus infection and occurrence of complications was not related to young age.
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收藏
页码:717 / 721
页数:5
相关论文
共 19 条
  • [1] ARTIGAS NAMBRARD R, 1951, Rev Chil Pediatr, V22, P60
  • [2] Calico I, 1990, Enferm Infecc Microbiol Clin, V8, P406
  • [3] Lack of association between rotavirus infection and intussusception: implications for use of attenuated rotavirus vaccines
    Chang, EJ
    Zangwill, KM
    Lee, H
    Ward, JI
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2002, 21 (02) : 97 - 102
  • [4] Intussusception, rotavirus diarrhea, and rotavirus vaccine use among children in New York State
    Chang, HGH
    Smith, PF
    Ackelsberg, J
    Morse, DL
    Glass, RI
    [J]. PEDIATRICS, 2001, 108 (01) : 54 - 60
  • [5] Garcia C, 1997, REV MED CHILE, V125, P54
  • [6] Intussusception, infection, and immunization Summary of a workshop on rotavirus
    Kombo, LA
    Gerber, MA
    Pickering, LK
    Atreya, CD
    Breiman, RF
    [J]. PEDIATRICS, 2001, 108 (02)
  • [7] KONNO T, 1978, J MED VIROL, V2, P265, DOI 10.1002/jmv.1890020310
  • [8] *MIN COOP PLAN GOB, CAR SOC NAC CASEN
  • [9] Montes P, 2000, REV MED CHILE, V128, P309
  • [10] INTUSSUSCEPTION, ADENOVIRUS, AND CHILDREN - A BRIEF REAFFIRMATION
    MONTGOMERY, EA
    POPEK, EJ
    [J]. HUMAN PATHOLOGY, 1994, 25 (02) : 169 - 174