Vascular calcification in middle age and long-term risk of hip fracture: The Framingham Study

被引:55
作者
Samelson, Elizabeth J.
Cupples, L. Adrienne
Broe, Kerry E.
Hannan, Marian T.
O'Donnell, Christopher J.
Kiel, Douglas P.
机构
[1] Inst Aging Res Hebrew SeniorLife, Boston, MA 02131 USA
[2] Harvard Univ, Sch Med, Dept Med, Boston, MA USA
[3] NHLBI Framingham Heart Study, Framingham, MA USA
关键词
hip fracture; men; osteoporosis; population studies; vascular calcification; women;
D O I
10.1359/JBMR.070519
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Osteoporosis and atherosclerosis frequently occur in the same individuals and may share similar pathogenic mechanisms. This study examined the relation between severity of aortic calcification in middleage years and subsequent risk of hip fracture in women and men in the population-based Framingham Study.
引用
收藏
页码:1449 / 1454
页数:6
相关论文
共 37 条
  • [1] Vascular calcification - Mechanisms and clinical ramifications
    Abedin, M
    Tintut, Y
    Demer, LL
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (07) : 1161 - 1170
  • [2] ABELL LL, 1952, J BIOL CHEM, V195, P357
  • [3] [Anonymous], 1951, AM J PUBLIC HEALTH
  • [4] Radiographic measure of aorta calcification is a site-specific predictor of bone loss and fracture risk at the hip
    Bagger, Y. Z.
    Tanko, L. B.
    Alexandersen, P.
    Qin, G.
    Christiansen, C.
    [J]. JOURNAL OF INTERNAL MEDICINE, 2006, 259 (06) : 598 - 605
  • [5] EFFECT OF DEGENERATIVE SPINAL AND AORTIC CALCIFICATION ON BONE-DENSITY MEASUREMENTS IN POSTMENOPAUSAL WOMEN - LINKS BETWEEN OSTEOPOROSIS AND CARDIOVASCULAR-DISEASE
    BANKS, LM
    LEES, B
    MACSWEENEY, JE
    STEVENSON, JC
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1994, 24 (12) : 813 - 817
  • [6] Osteoporosis and coronary atherosclerosis in asymptomatic postmenopausal women
    Barengolts, EI
    Berman, M
    Kukreja, SC
    Kouznetsova, T
    Lin, C
    Chomka, EV
    [J]. CALCIFIED TISSUE INTERNATIONAL, 1998, 62 (03) : 209 - 213
  • [7] ASSOCIATION BETWEEN LOW BONE-DENSITY AND STROKE IN ELDERLY WOMEN - THE STUDY OF OSTEOPOROTIC FRACTURES
    BROWNER, WS
    PRESSMAN, AR
    NEVITT, MC
    CAULEY, JA
    CUMMINGS, SR
    [J]. STROKE, 1993, 24 (07) : 940 - 946
  • [8] Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass
    Ensrud, KE
    Thompson, DE
    Cauley, JA
    Nevitt, MC
    Kado, DM
    Hochberg, MC
    Santora, AC
    Black, DM
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (03) : 241 - 249
  • [9] A role for Smad6 in development and homeostasis of the cardiovascular system
    Galvin, KM
    Donovan, MJ
    Lynch, CA
    Meyer, RI
    Paul, RJ
    Lorenz, JN
    Fairchild-Huntress, V
    Dixon, KL
    Dunmore, JH
    Gimbrone, MA
    Falb, D
    Huszar, D
    [J]. NATURE GENETICS, 2000, 24 (02) : 171 - 174
  • [10] Progression of aortic calcification is associated with metacarpal bone loss during menopause - A population-based longitudinal study
    Hak, AE
    Pols, HAP
    van Hemert, AM
    Hofman, A
    Witteman, JCM
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2000, 20 (08) : 1926 - 1931