Secretin in a patient with treatment-resistant schizophrenia and prominent autistic features

被引:18
作者
Alamy, SS
Jarskog, LF
Sheitman, BB
Lieberman, JA
机构
[1] Univ N Carolina, Sch Med, Dept Psychiat, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Sch Med, UNC Schizophrenia Res Ctr, Chapel Hill, NC 27599 USA
[3] Dorothea Dix Hosp, Raleigh, NC USA
关键词
secretin; schizophrenia; autism; treatment-resistant; neurodevelopment;
D O I
10.1016/j.schres.2003.07.003
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Secretin, a gastrointestinal (GI) peptide, may offer therapeutic benefit in autism. Autistic features can also be present in schizophrenia and a recent study suggested a role for adjunctive secretin in treatment-resistant schizophrenia. The current report describes one patient with undifferentiated schizophrenia and prominent autistic features who received a single dose of secretin and demonstrated substantial yet transient improvement. The case illustrates the potential role of secretin as a novel adjunctive treatment strategy in schizophrenic patients with autistic features. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:183 / 186
页数:4
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