A practical guide to arylbiguanides - Synthesis and structural characterization

被引：36

作者：

LeBel, O ^{[1
]}

Maris, T ^{[1
]}

Duval, H ^{[1
]}

Wuest, JD ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2005年 / 83卷 / 6-7期

关键词：

biguanide; biguanidinium; synthesis; structure; hydrogen bonds; noncovalent interactions; supramolecular chemistry;

D O I：

10.1139/v05-093

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Monohydrochloride salts of diverse 1-arylbiguanides and 1,5-diarylbiguanides were synthesized by the reaction of anilinium chlorides with dicyandiamide or sodium dicyanamide, and the biguanidinium chlorides were converted into the corresponding biguanides by deprotonation with methanolic NaOCH3. The resulting biguanides and their salts were fully characterized by spectroscopic methods, and the structures of representative compounds were determined by X-ray crystallography.

引用

页码：615 / 625

页数：11

共 46 条

[1]

AMIG, 1985, B SOC CHIM BELG, V94, P119

[2] MOLECULAR-STRUCTURE OF 1-(2-SULFOETHYL)BIGUANIDE [J].