Neurodegeneration and the neuroimmune system

被引：32

作者：

El Khoury, Joseph ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Lab Innate Immun & Neuroimmunol, Ctr Immunol & Inflammatory Dis, Charlestown, MA USA

[2] Harvard Univ, Sch Med, Charlestown, MA USA

来源：

NATURE MEDICINE | 2010年 / 16卷 / 12期

关键词：

MILD COGNITIVE IMPAIRMENT; MICROGLIAL ACTIVATION; ALZHEIMER-DISEASE; BETA; ADJUVANT; MODELS; BRAIN;

D O I：

10.1038/nm1210-1369

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1369 / 1370

页数：2

共 24 条

[1] Immune blood biomarkers of Alzheimer disease patients [J].

Avagyan, Hripsime ;

Goldenson, Ben ;

Tse, Eric ;

Masoumi, Ava ;

Porter, Verna ;

Wiedau-Pazos, Martina ;

Sayre, James ;

Ong, Reno ;

Mahanian, Michelle ;

Koo, Patrick ;

Bae, Susan ;

Micic, Miodrag ;

Liu, Philip T. ;

Rosenthal, Mark J. ;

Fiala, Milan .

JOURNAL OF NEUROIMMUNOLOGY, 2009, 210 (1-2) :67-72

[2] Biomarkers in Alzheimer's disease drug development [J].

Blennow, Kaj .

NATURE MEDICINE, 2010, 16 (11) :1218-1222

[3] Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy [J].

Cartier, Nathalie ;

Hacein-Bey-Abina, Salima ;

Bartholomae, Cynthia C. ;

Veres, Gabor ;

Schmidt, Manfred ;

Kutschera, Ina ;

Vidaud, Michel ;

Abel, Ulrich ;

Dal-Cortivo, Liliane ;

Caccavelli, Laure ;

Mahlaoui, Nizar ;

Kiermer, Veronique ;

Mittelstaedt, Denice ;

Bellesme, Celine ;

Lahlou, Najiba ;

Lefrere, Francois ;

Blanche, Stephane ;

Audit, Muriel ;

Payen, Emmanuel ;

Leboulch, Philippe ;

l'Homme, Bruno ;

Bougneres, Pierre ;

Von Kalle, Christof ;

Fischer, Alain ;

Cavazzana-Calvo, Marina ;

Aubourg, Patrick .

SCIENCE, 2009, 326 (5954) :818-823

[4] Alzheimer's disease: strategies for disease modification [J].

Citron, Martin .

NATURE REVIEWS DRUG DISCOVERY, 2010, 9 (05) :387-398

[5] Pittsburgh Compound B (11C-PIB) and Fluorodeoxyglucose (18F-FDG) PET in Patients With Alzheimer Disease, Mild Cognitive Impairment, and Healthy Controls [J].

Devanand, D. P. ;

Mikhno, Arthur ;

Pelton, Gregory H. ;

Cuasay, Katrina ;

Pradhaban, Gnanavalli ;

Kumar, J. S. Dileep ;

Upton, Neil ;

Lai, Robert ;

Gunn, Roger N. ;

Libri, V. ;

Liu, Xinhua ;

van Heertum, Ronald ;

Mann, J. John ;

Parsey, Ramin V. .

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 2010, 23 (03) :185-198

[6] CD36 mediates the innate host response to β-amyloid [J].

El Khoury, JB ;

Moore, KJ ;

Means, TK ;

Leung, J ;

Terada, K ;

Toft, M ;

Freeman, MW ;

Luster, AD .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (12) :1657-1666

[7] Ineffective phagocytosis of amyloid-β by macrophages of Alzheimer's disease patients [J].

Fiala, M ;

Lin, J ;

Ringman, J ;

Kermani-Arab, V ;

Tsao, G ;

Patel, A ;

Lossinsky, AS ;

Graves, MC ;

Gustavson, A ;

Sayre, J ;

Sofroni, E ;

Suarez, T ;

Chiappelli, F ;

Bernard, G .

JOURNAL OF ALZHEIMERS DISEASE, 2005, 7 (03) :221-232

[8] Bridging the Valley of Death of therapeutics for neurodegeneration [J].

Finkbeiner, Steven .

NATURE MEDICINE, 2010, 16 (11) :1227-1232

[9]

Frenkel D, 2005, CLIN IMMUNOL, V115, pS24

[10] A nasal proteosome adjuvant activates microglia and prevents amyloid deposition [J].

Frenkel, Dan ;

Puckett, Lindsay ;

Petrovic, Sanja ;

Xia, Weiming ;

Chen, Guiquan ;

Vega, Jose ;

Dembinsky-Vaknin, Adi ;

Shen, Jie ;

Plante, Martin ;

Burt, David S. ;

Weiner, Howard L. .

ANNALS OF NEUROLOGY, 2008, 63 (05) :591-601

← 1 2 3 →