Sequence polymorphisms in pfcrt are strongly associated with chloroquine resistance in Plasmodium falciparum

被引:56
作者
Chen, N [1 ]
Russell, B [1 ]
Staley, J [1 ]
Kotecka, B [1 ]
Nasveld, P [1 ]
Cheng, Q [1 ]
机构
[1] Australian Army Malaria Inst, Dept Parasitol, Enoggera, Qld 4051, Australia
关键词
D O I
10.1086/320206
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1543 / 1545
页数:3
相关论文
共 7 条
[1]   Association of cg2 and pfmdr1 genotype with chloroquine resistance in field samples of Plasmodium falciparum from Nigeria [J].
Adagu, IS ;
Warhurst, DC .
PARASITOLOGY, 1999, 119 :343-348
[2]   Chloroquine resistance in Plasmodium falciparum and polymorphism of the CG2 gene [J].
Basco, LK ;
Ringwald, P .
JOURNAL OF INFECTIOUS DISEASES, 1999, 180 (06) :1979-1986
[3]   Molecular epidemiology of malaria in Yaounde, Cameroon V.: Analysis of the omega repetitive region of the Plasmodium falciparum CG2 gene and chloroquine resistance [J].
Basco, LK ;
Ringwald, P .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1999, 61 (05) :807-813
[4]   Analysis of κ and ω repeats of the cg2 gene and chloroquine susceptibility in isolates of Plasmodium fulciparum from sub-Saharan Africa [J].
Durand, R ;
Gabbett, E ;
Di Piazza, JP ;
Delabre, JF ;
Le Bras, J .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1999, 101 (1-2) :185-197
[5]  
Fidock DA, 2000, MOL CELL, V6, P861, DOI 10.1016/S1097-2765(05)00077-8
[6]  
RIECKMANN KH, 1978, LANCET, V1, P22
[7]   Complex polymorphisms in an similar to 330 kDa protein are linked to chloroquine-resistant P-falciparum in Southeast Asia and Africa [J].
Su, XZ ;
Kirkman, LA ;
Fujioka, H ;
Wellems, TE .
CELL, 1997, 91 (05) :593-603