Collagen receptor signalling in platelets: extending the role of the ITAM

被引：164

作者：

Watson, SP

Gibbins, J

机构：

[1] Univ Oxford, Dept Pharmacol, Oxford OX1 3QT, England

[2] Univ Reading, Sch Anim & Microbial Sci, Reading RG6 6AA, Berks, England

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0167-5699(98)01267-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent studies have shown that activation of platelets by collagen is mediated through the same pathway as that used by immune receptors, with pivotal roles for an immunoreceptor tyrosine-based activation motif (ITAM) sequence on the Fc receptor gamma-chain and the tyrosine kinase Syk. Here, Steve Watson and Jonathan Gibbins discuss the implication for the physiological and pathological regulation of blood platelets.

引用

页码：260 / 264

页数：5

共 50 条

[1] PLATELETS WITH 10-PERCENT OF THE NORMAL AMOUNT OF GLYCOPROTEIN-VI HAVE AN IMPAIRED RESPONSE TO COLLAGEN THAT RESULTS IN A MILD BLEEDING TENDENCY
ARAI, M
YAMAMOTO, N
MOROI, M
AKAMATSU, N
FUKUTAKE, K
TANOUE, K
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 1995, 89 (01) : 124 - 130
[2] Collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma 2 in platelets independent of the integrin alpha(2)beta(1)
Asselin, J
Gibbins, JM
Achison, M
Lee, YH
Morton, LF
Farndale, RW
Barnes, MJ
Watson, SP
[J]. BLOOD, 1997, 89 (04) : 1235 - 1242
[3] ACTIVATION OF HUMAN PLATELETS BY PEROXOVANADATE IS ASSOCIATED WITH TYROSINE PHOSPHORYLATION OF PHOSPHOLIPASE C-GAMMA AND FORMATION OF INOSITOL PHOSPHATES
BLAKE, RA
WALKER, TR
WATSON, SP
[J]. BIOCHEMICAL JOURNAL, 1993, 290 : 471 - 475
[4] FC-GAMMA RECEPTOR-II STIMULATED FORMATION OF INOSITOL PHOSPHATES IN HUMAN PLATELETS IS BLOCKED BY TYROSINE KINASE INHIBITORS AND ASSOCIATED WITH TYROSINE PHOSPHORYLATION OF THE RECEPTOR
BLAKE, RA
ASSELIN, J
WALKER, T
WATSON, SP
[J]. FEBS LETTERS, 1994, 342 (01): : 15 - 18
[5] COLLAGEN STIMULATES TYROSINE PHOSPHORYLATION OF PHOSPHOLIPASE C-GAMMA-2 BUT NOT PHOSPHOLIPASE C-GAMMA-1 IN HUMAN PLATELETS
BLAKE, RA
SCHIEVEN, GL
WATSON, SP
[J]. FEBS LETTERS, 1994, 353 (02) : 212 - 216
[6] Cloning, characterization, and functional studies of a nonintegrin platelet receptor for type I collagen
Chiang, TM
Rinaldy, A
Kang, AH
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (03) : 514 - 521
[7] COLLER BS, 1989, BLOOD, V74, P182
[8] EVIDENCE FOR A ROLE FOR TYROSINE PHOSPHORYLATION OF PHOSPHOLIPASE C-GAMMA-2 IN COLLAGEN-INDUCED PLATELET CYTOSOLIC CALCIUM MOBILIZATION
DANIEL, JL
DANGELMAIER, C
SMITH, JB
[J]. BIOCHEMICAL JOURNAL, 1994, 302 : 617 - 622
[9] DISTURBED PLATELET-AGGREGATION TO COLLAGEN ASSOCIATED WITH AN ANTIBODY AGAINST AN 85-KD TO 90-KD PLATELET GLYCOPROTEIN IN A PATIENT WITH PROLONGED BLEEDING-TIME
DECKMYN, H
VANHOUTTE, E
VERMYLEN, J
[J]. BLOOD, 1992, 79 (06) : 1466 - 1471
[10] Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets
Gibbins, J
Asselin, J
Farndale, R
Barnes, M
Law, CL
Watson, SP
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (30) : 18095 - 18099

← 1 2 3 4 5 →