Vitamin D and Cardiovascular Disease: A Novel Agent for Reducing Cardiovascular Risk?

被引：48

作者：

Anagnostis, Panagiotis ^{[1
]}

Athyros, Vasilios G. ^{[2
]}

Adamidou, Fotini ^{[1
]}

Florentin, Matilda ^{[3
]}

Karagiannis, Asterios ^{[2
]}

机构：

[1] Hippokrateion Hosp, Endocrinol Clin, Thessaloniki 54642, Greece

[2] Aristotle Univ Thessaloniki, Hippokrat Hosp, Propedeut Dept Internal Med 2, GR-54006 Thessaloniki, Greece

[3] UCL, Univ Coll London Med Sch, Vasc Prevent Clin, Dept Clin Biochem, London, England

来源：

CURRENT VASCULAR PHARMACOLOGY | 2010年 / 8卷 / 05期

关键词：

Vitamin D; cardiovascular disease; hypertension; diabetes mellitus; metabolic syndrome; NUTRITION EXAMINATION SURVEY; PARATHYROID-HORMONE LEVELS; ISCHEMIC-HEART-DISEASE; SMOOTH-MUSCLE-CELLS; 3RD NATIONAL-HEALTH; PERIPHERAL ARTERIAL-DISEASE; TYPE-2; DIABETES-MELLITUS; RANDOMIZED CONTROLLED-TRIALS; RECEPTOR GENE POLYMORPHISMS; IMPAIRED GLUCOSE-TOLERANCE;

D O I：

10.2174/157016110792006978

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Vitamin D deficiency is a well-established risk factor for bone disease. Emerging data suggest a pleiotropic role of this agent in a variety of functions in humans. Epidemiological studies indicate an inverse association between vitamin D deficiency and the prevalence of cardiovascular disease (CVD), as well as individual cardiometabolic risk factors, such as hypertension, diabetes, dyslipidemia and the metabolic syndrome. Moreover, vitamin D deficiency has been implicated in the atherosclerotic process. This review considers current data regarding the role of vitamin D deficiency in the development of CVD and addresses the effect of supplementation on cardiovascular outcomes.

引用

页码：720 / 730

页数：11

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