Persistence of fetal hemoglobin production after successful transplantation of cord blood stem cells in a patient with sickle cell anemia

被引：39

作者：

Brichard, B ^{[1
]}

Vermylen, C ^{[1
]}

Ninane, J ^{[1
]}

Cornu, G ^{[1
]}

机构：

[1] UNIV LOUVAIN, DEPT PEDIAT HEMATOL, SCH MED, B-1200 BRUSSELS, BELGIUM

来源：

JOURNAL OF PEDIATRICS | 1996年 / 128卷 / 02期

关键词：

D O I：

10.1016/S0022-3476(96)70398-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A girl with sickle cell anemia was treated with cord blood transplantation combined with hematopoietic growth factor. Cord blood cells were collected from a sister with an identical human leukocyte antigen complex who was a carrier of the sickle cell trait (hemoglobin AS). The patient had complete engraftment and no graft-versus-host disease. The persistence of a high level of fetal hemoglobin 6 months after engraftment was noted.

引用

页码：241 / 243

页数：3

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