Serum thyroglobulin measurement -: Utility in clinical practice

被引：68

作者：

Torréns, JI

Burch, HB

机构：

[1] Walter Reed Army Med Ctr, Dept Med, Endocrine Metab Serv, Washington, DC 20307 USA

[2] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Div Endocrinol, Newark, NJ 07103 USA

[3] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2001年 / 30卷 / 02期

关键词：

D O I：

10.1016/S0889-8529(05)70194-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serum thyroglobulin levels play a crucial role in the diagnosis and management of several thyroid disorders. This is particularly the case in the management of patients with differentiated thyroid cancer. Rational interpretation of serum thyroglobulin (TG) levels requires a working knowledge of the serum TG assay and its limitations. The ability to stimulate TC with rhTSH during thyroid hormone suppression and to measure TG mRNA from peripheral blood holds promise for improvement in the management of thyroid cancer patients over the next decade. This article will review the clinical use of serum TG in several thyroid disorders, with particular emphasis on the management of differentiated thyroid cancer. Thyroglobulin assay limitations and potential solutions to these problems also are discussed.

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页码：429 / +

页数：40

相关论文

共 286 条

[1] THE RADIOACTIVE WIG IN I-131 WHOLE-BODY IMAGING [J].

ABDELDAYEM, HM ;

HALKER, K ;

ELSAYED, M .

CLINICAL NUCLEAR MEDICINE, 1984, 9 (08) :454-455

[2]

ACHONG DM, 1991, J NUCL MED, V32, P2275

[3] RADIOACTIVE IODINE UPTAKE BY A LARGE CELL UNDIFFERENTIATED BRONCHOGENIC-CARCINOMA [J].

ACOSTA, J ;

CHITKARA, R ;

KHAN, F ;

AZUETA, V ;

SILVER, L .

CLINICAL NUCLEAR MEDICINE, 1982, 7 (08) :368-369

[4] THYROGLOBULIN MEASUREMENT VS I-131 TOTAL-BODY SCAN FOR FOLLOW-UP OF WELL-DIFFERENTIATED THYROID-CANCER [J].

AIELLO, DP ;

MANNI, A .

ARCHIVES OF INTERNAL MEDICINE, 1990, 150 (02) :437-439

[5] I-131 uptake in the breast for thyroid cancer surveillance with biopsy-proven benign tissue [J].

Allen, T ;

Wiest, P ;

Vela, S ;

Hartshorne, M ;

Crooks, LA .

CLINICAL NUCLEAR MEDICINE, 1998, 23 (09) :585-587

[6]

AMINO N, 1986, THYROID, P546

[7] ROLE OF NECK ULTRASONOGRAPHY IN THE FOLLOW-UP OF PATIENTS OPERATED ON FOR THYROID-CANCER [J].

ANTONELLI, A ;

MICCOLI, P ;

FERDEGHINI, M ;

DICOSCIO, G ;

ALBERTI, B ;

IACCONI, P ;

BALDI, V ;

FALLAHI, P ;

BASCHIERI, L .

THYROID, 1995, 5 (01) :25-28

[8] Early diagnosis by genetic analysis of differentiated thyroid cancer metastases in small lymph nodes [J].

Arturi, F ;

Russo, D ;

Giuffrida, D ;

Ippolito, A ;

Perrotti, N ;

Vigneri, R ;

Filetti, S .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (05) :1638-1641

[9] THE COMPARATIVE VALUE OF SERUM THYROGLOBULIN MEASUREMENTS AND I-131 TOTAL-BODY SCANS IN THE FOLLOW-UP-STUDY OF PATIENTS WITH TREATED DIFFERENTIATED THYROID-CANCER [J].

ASHCRAFT, MW ;

VANHERLE, AJ .

AMERICAN JOURNAL OF MEDICINE, 1981, 71 (05) :806-814

[10] MAPPING OF HUMAN THYROGLOBULIN GENE ON THE LONG ARM OF CHROMOSOME-8 BY INSITU HYBRIDIZATION [J].

AVVEDIMENTO, VE ;

DILAURO, R ;

MONTICELLI, A ;

BERNARDI, F ;

PATRACCHINI, P ;

CALZOLARI, E ;

MARTINI, G ;

VARRONE, S .

HUMAN GENETICS, 1985, 71 (02) :163-166

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