Mathematical model - tell us the future!

被引：12

作者：

Huovinen, P

机构：

[1] Antimicrobial Research Laboratory, Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Turku

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2005年 / 56卷 / 02期

关键词：

resistance; surveillance; antibiotic consumption; mathematical models;

D O I：

10.1093/jac/dki230

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Studying bacterial resistance has direct importance for the antimicrobial treatment of individual patients. In addition, surveillance data pooled from individual diagnostic reports help physicians to choose the most effective drug for empirical therapy. However, this is not the limit of what can be done with the resistance data. There is an increasing need to synthesize the available strands of data in order to construct mathematical models that can be used as tools to predict the likely outcomes of various antibiotic policy options.

引用

页码：257 / 258

页数：2

共 24 条

[1] Persistence of antibiotic resistant bacteria [J].

Andersson, DI .

CURRENT OPINION IN MICROBIOLOGY, 2003, 6 (05) :452-456

[2]

Arason VA, 1996, BMJ-BRIT MED J, V313, P387

[3] The transmission dynamics of antibiotic-resistant bacteria: the relationship between resistance in commensal organisms and antibiotic consumption [J].

Austin, DJ ;

Kakehashi, M ;

Anderson, RM .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1997, 264 (1388) :1629-1638

[4] The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance [J].

Austin, DJ ;

Kristinsson, KG ;

Anderson, RM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (03) :1152-1156

[5] Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals [J].

Bergstrom, CT ;

Lo, M ;

Lipsitch, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (36) :13285-13290

[6] Understanding the spread of antibiotic resistant pathogens in hospitals: Mathematical models as tools for control [J].

Bonten, MJM ;

Austin, DJ ;

Lipsitch, M .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (10) :1739-1746

[7] Variation in antibiotic use in the European Union [J].

Cars, O ;

Mölstad, S ;

Melander, A .

LANCET, 2001, 357 (9271) :1851-1853

[8] Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction [J].

Enne, VI ;

Livermore, DM ;

Stephens, P ;

Hall, LMC .

LANCET, 2001, 357 (9265) :1325-1328

[9] Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. [J].

Goossens, H ;

Ferech, M ;

Stichele, RV ;

Elseviers, M .

LANCET, 2005, 365 (9459) :579-587

[10] Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers [J].

Gustafsson, I ;

Cars, O ;

Andersson, DI .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 52 (02) :258-263

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