A mild and facile reduction of azides to amines by N,N-dimethylhydrazine and catalytic ferric chloride

被引：17

作者：

Kamal, A ^{[1
]}

Reddy, BSN ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

CHEMISTRY LETTERS | 1998年 / 07期

关键词：

D O I：

10.1246/cl.1998.593

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of a variety of azido compounds with N,N-dimethylhydrazine in the presence of a catalytic amount of ferric chloride hexahydrate in methanol results in excellent yields of the corresponding amino compounds. This reductive system is compatible with a wide assortment of functional groups and has also been extended towards the synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics.

引用

页码：593 / 594

页数：2

共 27 条

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