Immunohistochemical detection of virulence-associated antigens of Rhodococcus equi in pulmonary lesions of foals

被引：26

作者：

Madarame, H

Takai, S

Morisawa, N

Fujii, M

Hidaka, D

Tsubaki, S

Hasegawa, Y

机构：

[1] Dept. of Laboratory Animal Science, Sch. of Vet. Med. and Anim. Sciences, Kitasato University, Towada

来源：

VETERINARY PATHOLOGY | 1996年 / 33卷 / 03期

关键词：

horses; immunohistochemistry; lung; Rhodococcus equi;

D O I：

10.1177/030098589603300312

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Rhodococcus equi was isolated from the lungs of six foals with bronchopneumonia. All isolates expressed 15-17-kd antigens by immunoblot analysis and contained a virulence-associated plasmid of 85 or 90 kb. Immunohistochemically, R. equi from all pulmonary lesions showed the expression of 15-17-kd antigens mainly in the phagocytic cells. The specific monoclonal antibody to 15-17-kd antigens of R. equi (MAb 10G5) may be an aid in the diagnosis of R. equi-induced pneumonia.

引用

页码：341 / 343

页数：3

共 10 条

[1]

Barton M. D., 1980, Veterinary Bulletin, V50, P65

[2]

DUNGWORTH DL, 1993, PATHOLOGY DOMESTIC A, P652

[3] IMMUNOHISTOCHEMICAL OBSERVATIONS ON PNEUMONIC LESIONS CAUSED BY RHODOCOCCUS-EQUI IN FOALS [J].