Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

被引:228
作者
Yu, Fei [1 ]
Du, Lanying [2 ]
Ojcius, David M. [3 ]
Pan, Chungen [4 ]
Jiang, Shibo [2 ,5 ]
机构
[1] Hebei Agr Univ, Coll Life & Sci, Baoding, Peoples R China
[2] New York Blood Ctr, Lindsley Kimball Res Inst, New York, NY 10021 USA
[3] Univ Pacific, Sch Dent, Dept Biomed Sci, San Francisco, CA 94115 USA
[4] Guangdong Haid Grp Co Ltd, Haid Res Inst, Guangdong Haid Inst Anim Husb & Vet, Guangzhou, Peoples R China
[5] Fudan Univ, Sch Basic Med Sci, Key Lab Med Mol Virol MOE NHC CAMS, Shanghai, Peoples R China
关键词
2019-nCoV; Diagnosis; Preventive; Therapeutic; EAST RESPIRATORY SYNDROME; RECEPTOR-BINDING DOMAIN; HUMAN MONOCLONAL-ANTIBODIES; SPIKE PROTEIN; SARS-COV; MERS-COV; NEUTRALIZING ANTIBODY; POSTEXPOSURE EFFICACY; CROSS-NEUTRALIZATION; FUNCTIONAL RECEPTOR;
D O I
10.1016/j.micinf.2020.01.003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
On 10 January 2020, a new coronavirus causing a pneumonia outbreak in Wuhan City in central China was denoted as 2019-nCoV by the World Health Organization (WHO). As of 24 January 2020, there were 887 confirmed cases of 2019-nCoV infection, including 26 deaths, reported in China and other countries. Therefore, combating this new virus and stopping the epidemic is a matter of urgency. Here, we focus on advances in research and development of fast diagnosis methods, as well as potential prophylactics and therapeutics to prevent or treat 2019-nCoV infection. (C) 2020 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:74 / 79
页数:6
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