Lymphomas and oncolytic virus therapy

被引：4

作者：

Alain, T

Thirukkumaran, C

Morris, DG

Urbanski, SJ

Janowska-Wieczorek, A

Lee, PWK

Kossakowska, AE

机构：

[1] Univ Calgary, Canc Biol Res Grp, Calgary, AB T2N 1N4, Canada

[2] Univ Calgary, Dept Pathol, Calgary, AB T2N 1N4, Canada

[3] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB T2N 1N4, Canada

[4] Calgary Lab Serv, Calgary, AB, Canada

[5] Tom Baker Canc Clin, Calgary, AB, Canada

[6] Univ Alberta, Dept Med, Edmonton, AB T6G 2M7, Canada

[7] Canadian Blood Serv, Edmonton, AB, Canada

来源：

CLINICAL LYMPHOMA | 2003年 / 4卷 / 02期

关键词：

autotransplant; cytotoxicity; G207; herpes virus; ONYX-015;

D O I：

10.3816/CLM.2003.n.019

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with oncolytic viruses took place > 80 years ago; however, it achieved little success. With modern technologies and current knowledge of viruses and cancer, there is an expectation for the discovery of efficient oncolytic viral therapies. This article will review the current knowledge of oncolytic viruses in relation to the treatment of lymphoma.

引用

页码：104 / 111

页数：8

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