Proteome analysis of mesencephalic tissues: evidence for Parkinson's disease

被引:17
作者
Basso, M
Giraudo, S
Lopiano, L
Bergamasco, B
Bosticco, E
Cinquepalmi, A
Fasano, M
机构
[1] Univ Insubria, Dept Struct & Funct Biol, Busto Arsizio, VA, Italy
[2] Univ Insubria, Ctr Neurosci, Busto Arsizio, VA, Italy
[3] Univ Turin, Dept Neurosci, Turin, Italy
关键词
D O I
10.1007/s10072-003-0106-2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Proteome analysis is a powerful methodology to investigate protein expression in tissues involved in diseases not linked to particular genetic defects. To date, this technique has a limited number of applications in the field of neurodegenerative disorders. We decided therefore to investigate by this approach autoptic mesencephalic tissues of patients with idiopathic Parkinson's disease as well as control specimens from healthy subjects.
引用
收藏
页码:155 / 156
页数:2
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