Purification and characterization of enterocin 4, a bacteriocin produced by Enterococcus faecalis INIA 4

被引：55

作者：

Joosten, HMLJ

Nunez, M

Devreese, B

VanBeeumen, J

Marugg, JD

机构：

[1] INIA,CIT,DEPT TECNOL ALIMENTOS,MADRID 28040,SPAIN

[2] STATE UNIV GHENT,VAKGRP BIOCHEM FYSIOL & MICROBIOL,B-9000 GHENT,BELGIUM

[3] NETHERLANDS INST DAIRY RES,DEPT BIOPHYS CHEM,NL-6710 BA EDE,NETHERLANDS

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1996年 / 62卷 / 11期

关键词：

D O I：

10.1128/AEM.62.11.4220-4223.1996

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A simple two-step procedure was developed to obtain pure enterocin 4, a bacteriocin produced by Enterococcus faecalis INIA 4. Chemical and genetic characterization revealed that the primary structure of enterocin 4 is identical to that of peptide antibiotic AS-48 from Enterococcus faecalis S-48. In contrast to the reported inhibitory spectrum of AS-48, enterocin 4 displayed no activity against gram-negative bacteria.

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页码：4220 / 4223

页数：4

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