Iron Imports. I. Intestinal iron absorption and its regulation

被引：84

作者：

Frazer, DM ^{[1
]}

Anderson, GJ ^{[1
]}

机构：

[1] Queensland Inst Med Res, PO Royal Brisbane Hosp, Iron Metab Lab, Brisbane, Qld 4029, Australia

来源：

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY | 2005年 / 289卷 / 04期

关键词：

hepcidin; hemojuvelin; HFE; transferrin receptor 2;

D O I：

10.1152/ajpgi.00220.2005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Our knowledge of how the body absorbs iron from the diet and how this process is controlled has increased at a rapid rate in recent years. The identification of key molecules, including the iron regulatory peptide hepcidin, and the analysis of how they are regulated and interact have led to the development of an integrated model for the control of iron absorption by body iron requirements. Research now focuses on the role of the liver as the primary regulator of iron absorption, and this review considers some of the recent highlights and controversies in this area.

引用

页码：G631 / G635

页数：5

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