Vagus nerve stimulation for the treatment of bilateral independent temporal lobe epilepsy

被引：42

作者：

Alsaadi, TM

Laxer, KD

Barbaro, JM

Marks, WJ

Garcia, PA

机构：

[1] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA

来源：

EPILEPSIA | 2001年 / 42卷 / 07期

关键词：

vagus nerve stimulation; bilateral independent temporal lobe epilepsy;

D O I：

10.1046/j.1528-1157.2001.042007954.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose: We studied the effect of vagus nerve stimulation (VNS) on seizure reduction in patients with intractable epilepsy with bilateral independent temporal lobe foci. Methods: Ten patients who met the criterion of the presence of two distinctive clinical and ictal EEG seizure patterns were identified and followed up for 1 year. Results: Six patients had > 50% reduction in their seizure frequency that persisted up to = I year of follow-up, whereas four patients reported small or no reduction in their partial seizures. Conclusions: VNS is often effective and well tolerated in this select group of intractable epilepsy patients.

引用

收藏

页码：954 / 956

页数：3

相关论文

共 10 条

[1]

Garcia Paul A., 1996, Neurology, V46, pA243

[2] Vagus nerve stimulation therapy for partial-onset seizures - A randomized active-control trial [J].

Handforth, A ;

DeGiorgio, CM ;

Schachter, SC ;

Uthman, BM ;

Naritoku, DK ;

Tecoma, ES ;

Henry, TR ;

Collins, SD ;

Vaughn, BV ;

Gilmartin, RC ;

Labar, DR ;

Morris, GL ;

Salinsky, MC ;

Osorio, I ;

Ristanovic, RK ;

Labiner, DM ;

Jones, JC ;

Murphy, JV ;

Ney, GC ;

Wheless, JW .

NEUROLOGY, 1998, 51 (01) :48-55

[3] COMPARISON OF BITEMPORAL AND UNITEMPORAL EPILEPSY DEFINED BY DEPTH ELECTROENCEPHALOGRAPHY [J].

HIRSCH, LJ ;

SPENCER, SS ;

WILLIAMSON, PD ;

SPENCER, DD ;

MATTSON, RH .

ANNALS OF NEUROLOGY, 1991, 30 (03) :340-346

[4] TEMPORAL LOBECTOMY IN PATIENTS WITH BITEMPORAL EPILEPSY DEFINED BY DEPTH ELECTROENCEPHALOGRAPHY [J].

HIRSCH, LJ ;

SPENCER, SS ;

SPENCER, DD ;

WILLIAMSON, PD ;

MATTSON, RH .

ANNALS OF NEUROLOGY, 1991, 30 (03) :347-356

[5] BILATERAL HIPPOCAMPAL ATROPHY IN MEDIAL TEMPORAL-LOBE EPILEPSY [J].

KING, D ;

SPENCER, SS ;

MCCARTHY, G ;

LUBY, M ;

SPENCER, DD .

EPILEPSIA, 1995, 36 (09) :905-910

[6] Long-term treatment with vague nerve stimulation in patients with refractory epilepsy [J].

Morris, GL ;

Mueller, WM .

NEUROLOGY, 1999, 53 (08) :1731-1735

[7] Vagus nerve stimulation for the treatment of medically intractable seizures - Results of a 1-year open-extension trial [J].

Salinsky, MC ;

Uthman, BM ;

Ristanovic, RK ;

Wernicke, JF ;

Tarver, WB ;

George, R ;

Sonnen, A ;

Upton, A ;

Salinsky, M ;

Ristanovic, R ;

Bergen, D ;

Mirza, W ;

Rosenfeld, W ;

Naritoku, D ;

ManonEspaillat, R ;

Barolat, G ;

Willis, J ;

Stefan, H ;

Treig, T ;

Hufnagel, A ;

Kuzniecky, R ;

Uthman, B ;

Wilder, BJ ;

Augustinsson, L ;

BenMenachem, F ;

Ramsay, E ;

Allen, J .

ARCHIVES OF NEUROLOGY, 1996, 53 (11) :1176-1180

[8] RESULTS OF SURGICAL-TREATMENT IN PATIENTS WITH BITEMPORAL EPILEPTIFORM ABNORMALITIES [J].

SO, N ;

OLIVIER, A ;

ANDERMANN, F ;

GLOOR, P ;

QUESNEY, LF .

ANNALS OF NEUROLOGY, 1989, 25 (05) :432-439

[9] COMBINED DEPTH AND SUBDURAL ELECTRODE INVESTIGATION IN UNCONTROLLED EPILEPSY [J].

SPENCER, SS ;

SPENCER, DD ;

WILLIAMSON, PD ;

MATTSON, R .

NEUROLOGY, 1990, 40 (01) :74-79

[10] Vagus nerve stimulation induces a sustained anticonvulsant effect [J].

Takaya, M ;

Terry, WJ ;

Naritoku, DK .

EPILEPSIA, 1996, 37 (11) :1111-1116