Light-Responsive Capture and Release of DNA in a Ternary Supramolecular Complex

被引:158
作者
Nalluri, Siva Krishna Mohan [1 ,2 ]
Voskuhl, Jens [1 ,2 ]
Bultema, Jelle B. [3 ]
Boekema, Egbert J. [3 ]
Ravoo, Bart Jan [1 ,2 ]
机构
[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany
[2] Univ Munster, Grad Sch Chem, D-48149 Munster, Germany
[3] Univ Groningen, Dept Biophys Chem, Groningen Biomol Sci & Biotechnol Inst, NL-9747 AG Groningen, Netherlands
关键词
azobenzenes; cyclodextrins; DNA; molecular recognition; vesicles; AMPHIPHILIC CYCLODEXTRINS; AZOBENZENE POLYMERS; ALPHA-CYCLODEXTRIN; MOLECULAR SHUTTLE; BILAYER VESICLES; GENE DELIVERY; TRANSFECTION; SURFACE; POLYETHYLENIMINE; NANOPARTICLES;
D O I
10.1002/anie.201103707
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The wavelength determines whether DNA is captured in a light-responsive ternary supramolecular complex or released (see scheme). The reversible binding of DNA is triggered by a photoisomerization, which switches the complex from a multivalent to a monovalent binding mode. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:9747 / 9751
页数:5
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