Effect of fracture on bone turnover markers:: A longitudinal study comparing marker levels before and after injury in 113 elderly women

被引：123

作者：

Ivaska, Kaisa K. ^{[1
]}

Gerdhem, Paul

Akesson, Kristina

Garnero, Patrick

Obrant, Karl J.

机构：

[1] Malmo Univ Hosp, Dept Orthoped, Univ Lund, Clin & Mol Osteoporosis Res Unit, SE-20502 Malmo, Sweden

[2] Karnolinska Univ Hosp, Karolinska Inst, Dept Orthopaed, Stockholm, Sweden

[3] INSERM, Res Unit 664 & Synarc, F-69008 Lyon, France

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 08期

关键词：

bone turnover markers; fracture; fracture repair; longitudinal; prospective;

D O I：

10.1359/JBMR.070505

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

In this longitudinal, prospective, and population-based study (n = 1044), seven BTMs were assessed before and after trauma in 113 elderly women (85 with fractures). Markers were not altered in the immediate postfracture period but were clearly elevated during fracture repair. Recent fracture should thus be taken into account when markers are used in clinical practice.

引用

页码：1155 / 1164

页数：10

共 46 条

[1]

Fracture-induced changes in bone turnover:: a potential confounder in the use of biochemical markers in osteoporosis [J].