(i) Pathways and signalling molecules

被引：6

作者：

Nikolaou, V. S. ^{[1
]}

Tsiridis, E. ^{[1
]}

机构：

[1] Leeds Gen Infirm, Acad Dept Trauma & Orthopaed Surg, Clarendon Wing, Leeds LS2 9NS, W Yorkshire, England

来源：

CURRENT ORTHOPAEDICS | 2007年 / 21卷 / 04期

关键词：

bone; fracture; heating; enhancement; molecules;

D O I：

10.1016/j.cuor.2007.08.001

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Fracture heating is a complex and well orchestrated regenerative process, initiated in response to injury, resulting in optimal skeletal repair and restoration of skeletal function. Fracture heating remains to a great extent an unknown cascade, and recent developments in molecular biology have helped us to better understand the fracture heating cellular and molecular pathways. In this paper, we summarize the current knowledge of the most important molecules involved in the sequence of events during fracture heating, and we also focus on the latest research findings that will play important roles in the near future in better understanding fracture heating at the molecular level. (C) 2007 Published by Elsevier Ltd.

引用

页码：249 / 257

页数：9

共 73 条

[1] Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34) [J].