Mining the complexities of the estrogen signaling pathways for novel therapeutics

被引:33
作者
McDonnell, DP [1 ]
机构
[1] Duke Univ, Med Ctr, Durham, NC 27710 USA
关键词
D O I
10.1210/en.2003-0900
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:4237 / 4240
页数:4
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共 34 条
[1]   Molecular basis of agonism and antagonism in the oestrogen receptor [J].
Brzozowski, AM ;
Pike, ACW ;
Dauter, Z ;
Hubbard, RE ;
Bonn, T ;
Engstrom, O ;
Ohman, L ;
Greene, GL ;
Gustafsson, JA ;
Carlquist, M .
NATURE, 1997, 389 (6652) :753-758
[2]   ERβ has nongenomic action in caveolae [J].
Chambliss, KL ;
Yuhanna, IS ;
Anderson, RGW ;
Mendelsohn, ME ;
Shaul, PW .
MOLECULAR ENDOCRINOLOGY, 2002, 16 (05) :938-946
[3]   DEFINITION OF THE CRITICAL CELLULAR-COMPONENTS WHICH DISTINGUISH BETWEEN HORMONE AND ANTIHORMONE ACTIVATED PROGESTERONE-RECEPTOR [J].
CLEMM, DL ;
MACY, BL ;
SANTISOMERE, D ;
MCDONNELL, DP .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1995, 53 (1-6) :487-495
[4]   Estrogen receptor null mice: What have we learned and where will they lead us? [J].
Couse, JF ;
Korach, KS .
ENDOCRINE REVIEWS, 1999, 20 (03) :358-417
[5]   Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women [J].
Delmas, PD ;
Bjarnason, NH ;
Mitlak, BH ;
Ravoux, AC ;
Shah, AS ;
Huster, WJ ;
Draper, M ;
Christiansen, C .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (23) :1641-1647
[6]   Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene -: Results from a 3-year randomized clinical trial [J].
Ettinger, B ;
Black, DM ;
Mitlak, BH ;
Knickerbocker, RK ;
Nickelsen, T ;
Genant, HK ;
Christiansen, C ;
Delmas, PD ;
Zanchetta, JR ;
Stakkestad, J ;
Glüer, CC ;
Krueger, K ;
Cohen, FJ ;
Eckert, S ;
Ensrud, KE ;
Avioli, LV ;
Lips, P ;
Cummings, SR .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (07) :637-645
[7]   The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens [J].
Hall, JM ;
McDonnell, DP .
ENDOCRINOLOGY, 1999, 140 (12) :5566-5578
[8]   Evaluation of an estrogen receptor-β agonist in animal models of human disease [J].
Harris, HA ;
Albert, LM ;
Leathurby, Y ;
Malamas, MS ;
Mewshaw, RE ;
Miller, CP ;
Kharode, YP ;
Marzolf, J ;
Komm, BS ;
Winneker, RC ;
Frail, DE ;
Henderson, RA ;
Zhu, Y ;
Keith, JC .
ENDOCRINOLOGY, 2003, 144 (10) :4241-4249
[9]   Characterization of the biological roles of the estrogen receptors, ERα and ERβ, in estrogen target tissues in vivo through the use of an ERα-selective ligand [J].
Harris, HA ;
Katzenellenbogen, JA ;
Katzenellenbogen, BS .
ENDOCRINOLOGY, 2002, 143 (11) :4172-4177
[10]   Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein [J].
Herrington, DM ;
Howard, TD ;
Brosnihan, KB ;
McDonnell, DP ;
Li, XL ;
Hawkins, GA ;
Reboussin, DM ;
Xu, JF ;
Zheng, SQL ;
Meyers, DA ;
Bleecker, ER .
CIRCULATION, 2002, 105 (16) :1879-1882