Synthesis of substituted imidazopyrazines as ligands for the human somatostatin receptor subtype 5

被引：24

作者：

Contour-Galcéra, MO

Poitout, L

Moinet, C

Morgan, B

Gordon, T

Roubert, P

Thurieau, C

机构：

[1] Inst Henri Beaufour, F-91966 Les Ulis, France

[2] Biomeasure Inc, Milford, MA 01757 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0960-894X(01)00051-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new preparation of trisubstituted imidazopyrazines and dihydroimidazopyrazines via parallel synthesis using aminoacids and bromoketones resulted in the discovery of non-peptidic sst(5) selective agonists. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：741 / 745

页数：5

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