Chromatin structure depends on what's in the nucleosome's pocket

被引:8
作者
Caterino, Tamara L. [1 ]
Hayes, Jeffrey J. [1 ]
机构
[1] Univ Rochester, Med Ctr, Rochester, NY 14642 USA
关键词
D O I
10.1038/nsmb1107-1056
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two new studies point to a heretofore underappreciated mechanism by which chromatin higher-order structure can be regulated by surfaces in the nucleosome that are not associated with DNA.
引用
收藏
页码:1056 / 1058
页数:4
相关论文
共 16 条
[1]   SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays [J].
Angelov, D ;
Verdel, A ;
An, WJ ;
Bondarenko, V ;
Hans, F ;
Doyen, CM ;
Studitsky, VM ;
Hamiche, A ;
Roeder, RG ;
Bouvet, P ;
Dimitrov, S .
EMBO JOURNAL, 2004, 23 (19) :3815-3824
[2]   Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA [J].
Bao, YH ;
Konesky, K ;
Park, YJ ;
Rosu, S ;
Dyer, PN ;
Rangasamy, D ;
Tremethick, DJ ;
Laybourn, PJ ;
Luger, K .
EMBO JOURNAL, 2004, 23 (16) :3314-3324
[3]   The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA [J].
Barbera, AJ ;
Chodaparambil, JV ;
Kelley-Clarke, B ;
Joukov, V ;
Walter, JC ;
Luger, K ;
Kaye, KM .
SCIENCE, 2006, 311 (5762) :856-861
[4]   A charged and contoured surface on the nucleosome regulates chromatin compaction [J].
Chodaparambil, Jayanth V. ;
Barbera, Andrew J. ;
Lu, Xu ;
Kaye, Kenneth M. ;
Hansen, Jeffrey C. ;
Luger, Karolin .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (11) :1105-1107
[5]   Nucleosome arrays reveal the two-start organization of the chromatin fiber [J].
Dorigo, B ;
Schalch, T ;
Kulangara, A ;
Duda, S ;
Schroeder, RR ;
Richmond, TJ .
SCIENCE, 2004, 306 (5701) :1571-1573
[6]   Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome [J].
Doyen, Cecile-Marie ;
Montel, Fabien ;
Gautier, Thierry ;
Menoni, Herve ;
Claudet, Cyril ;
Delacour-Larose, Marlene ;
Angelov, Dimitri ;
Hamiche, Ali ;
Bednar, Jan ;
Faivre-Moskalenko, Cendrine ;
Bouvet, Philippe ;
Dimitrov, Stefan .
EMBO JOURNAL, 2006, 25 (18) :4234-4244
[7]   H2A.Z alters the nucleosome surface to promote HP1α-mediated chromatin fiber folding [J].
Fan, JY ;
Rangasamy, D ;
Luger, K ;
Tremethick, DJ .
MOLECULAR CELL, 2004, 16 (04) :655-661
[8]   MODULATION OF CHROMATIN FOLDING BY HISTONE ACETYLATION [J].
GARCIARAMIREZ, M ;
ROCCHINI, C ;
AUSIO, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (30) :17923-17928
[9]   Conformational dynamics of the chromatin fiber in solution: Determinants, mechanisms, and functions [J].
Hansen, JC .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2002, 31 :361-392
[10]   Crystal structure of the nucleosome core particle at 2.8 angstrom resolution [J].
Luger, K ;
Mader, AW ;
Richmond, RK ;
Sargent, DF ;
Richmond, TJ .
NATURE, 1997, 389 (6648) :251-260