Increasing Incidence of Streptococcus pneumoniae Serotype 19A and Emergence of Two Vaccine Escape Recombinant ST695 Strains in Liguria, Italy, 7 Years after Implementation of the 7-Valent Conjugated Vaccine

被引：23

作者：

Ansaldi, Filippo ^{[1
,2
]}

Canepa, Paola ^{[1
]}

de Florentiis, Daniela ^{[1
]}

Bandettini, Roberto ^{[3
]}

Durando, Paolo ^{[1
,2
]}

Icardi, Giancarlo ^{[1
,2
]}

机构：

[1] Univ Genoa, Dept Hlth Sci, I-16100 Genoa, Italy

[2] San Martino Univ Hosp, Genoa, Italy

[3] IRCCS Giannina Gaslini, Genoa, Italy

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2011年 / 18卷 / 02期

关键词：

IMPACT; CARRIAGE; CHILDREN; CLONES;

D O I：

10.1128/CVI.00383-10

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Two serotype 19A (ST695) Streptococcus pneumoniae vaccine escape recombinant strains attributable to capsular switching events were detected by a laboratory surveillance system that is an integral part of a vaccination program begun in Liguria, Italy, in May 2003, an Italian administrative region with long-lasting high coverage, an unusual occurrence in Europe. To our knowledge, this is the first detection of an occurrence of capsular switching outside the United States.

引用

页码：343 / 345

页数：3

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