Synthesis of irreversibly binding bicalutamide analogs for imaging studies

被引：14

作者：

Nair, VA

Mustafa, SM

Mohler, ML

Yang, J

Kirkovsky, LI

Dalton, JT

Miller, DD ^{[1
]}

机构：

[1] Ohio State Univ, Coll Pharm, Div Pharmaceut & Pharmaceut Chem, Columbus, OH 43210 USA

[2] Univ Tennessee, Ctr Hlth Sci, Dept Pharmaceut Sci, Memphis, TN 38163 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 28期

关键词：

bicalutamide; iodine; androgen; receptor; radioactive;

D O I：

10.1016/j.tetlet.2005.04.143

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic methodology for preparing radioactive androgen receptor binding compounds in order to determine receptor-ligands interactions has been developed. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4821 / 4823

页数：3

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