Biosynthesis of vitamins B-1 and B-6 in Escherichia coli: Concurrent incorporation of 1-deoxy-D-xylulose into thiamin (B-1) and pyridoxol (B-6)

被引：40

作者：

Himmeldirk, K

Kennedy, IA

Hill, RE

Sayer, BG

Spenser, ID

机构：

[1] MCMASTER UNIV,DEPT CHEM,HAMILTON,ON L8S 4M1,CANADA

[2] MCMASTER UNIV,DEPT PATHOL,HAMILTON,ON L8N 4Z5,CANADA

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 10期

关键词：

D O I：

10.1039/cc9960001187

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It is shown by C-13 NMR spectroscopy that, in Escherichia coli mutant WG2, the C-2,-3 bond of [2,3-C-13(2)]-1- deoxy-D-xylulose 2 enters C-4,-5 of the thiazole unit of thiamin (B-1) 1 and C-2,-3 of pyridoxol (B-6) 3, providing the first direct evidence that the intact C-5 chain of 1-deoxy-D-xylulose is incorporated concurrently into each of the two B Vitamins.

引用

页码：1187 / 1188

页数：2

共 11 条

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