Asymmetric epoxidation of a geminally-disubstituted and some trisubstituted enones catalysed by poly-L-leucine

被引：31

作者：

Bentley, PA ^{[1
]}

Bickley, JF ^{[1
]}

Roberts, SM ^{[1
]}

Steiner, A ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 22期

关键词：

epoxides; peptides and polypeptides; asymmetric reactions; asymmetric synthesis;

D O I：

10.1016/S0040-4039(01)00535-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Epoxidation of a range of enones derived from tetralone or related cyclic ketones, employing poly-L-leucine, urea-H2O2 and DBU in iso-propyl acetalte is reported. The corresponding epoxides were isolated in 63-85% yield and 59-96% ee. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3741 / 3743

页数：3

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