Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

被引:117
作者
Bell, Karen F. [1 ]
Al-Mubarak, Bashayer [1 ]
Fowler, Jill H. [2 ]
Baxter, Paul S. [1 ]
Gupta, Kunal [1 ]
Tsujita, Tadayuki [3 ]
Chowdhry, Sudhir [3 ]
Patani, Rickie [4 ]
Chandran, Siddharthan [4 ]
Horsburgh, Karen [2 ]
Hayes, John D. [3 ]
Hardingham, Giles E. [1 ]
机构
[1] Univ Edinburgh, Ctr Integrat Physiol, Edinburgh EH8 9XD, Midlothian, Scotland
[2] Univ Edinburgh, Ctr Cognit & Neural Syst, Edinburgh EH8 9JZ, Midlothian, Scotland
[3] Univ Dundee, Ninewells Hosp & Med Sch, Biomed Res Inst, Dundee DD1 9SY, Scotland
[4] Univ Edinburgh, Euan MacDonald Ctr MND Res, Edinburgh EH16 4SB, Midlothian, Scotland
基金
英国惠康基金; 英国医学研究理事会;
关键词
D O I
10.1073/pnas.1015229108
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
引用
收藏
页码:E1 / E2
页数:2
相关论文
共 5 条
[1]
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway [J].
Haskew-Layton, Renee E. ;
Payappilly, Jimmy B. ;
Smirnova, Natalya A. ;
Ma, Thong C. ;
Chan, Kelvin K. ;
Murphy, Timothy H. ;
Guo, Hengchang ;
Langley, Brett ;
Sultana, Rukhsana ;
Butterfield, D. Allan ;
Santagata, Sandro ;
Alldred, Melissa J. ;
Gazaryan, Irina G. ;
Bell, George W. ;
Ginsberg, Stephen D. ;
Ratan, Rajiv R. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (40) :17385-17390
[2]
MEASUREMENT OF STRIATAL H2O2 BY MICRODIALYSIS FOLLOWING GLOBAL FOREBRAIN ISCHEMIA AND REPERFUSION IN THE RAT - CORRELATION WITH THE CYTOTOXIC POTENTIAL OF H2O2 IN-VITRO [J].
HYSLOP, PA ;
ZHANG, ZY ;
PEARSON, DV ;
PHEBUS, LA .
BRAIN RESEARCH, 1995, 671 (02) :181-186
[3]
Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells [J].
Joannides, Alexis J. ;
Webber, Daniel J. ;
Raineteau, Olivier ;
Kelly, Claire ;
Irvine, Karen-Amanda ;
Watts, Colin ;
Rosser, Anne E. ;
Kemp, Paul J. ;
Blakemore, William F. ;
Compston, Alastair ;
Caldwell, Maeve A. ;
Allen, Nicholas D. ;
Chandran, Siddharthan .
BRAIN, 2007, 130 :1263-1275
[4]
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses [J].
Papadia, Sofia ;
Soriano, Francesc X. ;
Leveille, Frederic ;
Martel, Marc-Andre ;
Dakin, Kelly A. ;
Hansen, Henrik H. ;
Kaindl, Angela ;
Sifringer, Marco ;
Fowler, Jill ;
Stefovska, Vanya ;
Mckenzie, Grahame ;
Craigon, Marie ;
Corriveau, Roderick ;
Ghazal, Peter ;
Horsburgh, Karen ;
Yankner, Bruce A. ;
Wyllie, David J. A. ;
Ikonomidou, Chrysanthy ;
Hardingham, Giles E. .
NATURE NEUROSCIENCE, 2008, 11 (04) :476-487
[5]
Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione [J].
Soriano, Francesc X. ;
Leveille, Frederic ;
Papadia, Sofia ;
Higgins, Larry G. ;
Varley, James ;
Baxter, Paul ;
Hayes, John D. ;
Hardingham, Giles E. .
JOURNAL OF NEUROCHEMISTRY, 2008, 107 (02) :533-543