Digitalis and Na/Ca exchange: Old dog learns new mitochondrial tricks

被引:9
作者
Bers, Donald M. [1 ]
机构
[1] Univ Calif Davis, Dept Pharmacol, Davis, CA 95616 USA
关键词
CARDIAC MYOCYTES; CA2+ UPTAKE; INCREASES; TARGET;
D O I
10.1016/j.yjmcc.2010.08.004
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:713 / 714
页数:2
相关论文
共 12 条
[1]
Bers D., 2001, Excitation-Contraction Coupling and Cardiac Contractile Force, VVolume 237
[2]
Calcium/Calmodulin-dependent Kinase II Regulation of Cardiac Ion Channels [J].
Bers, Donald M. ;
Grandi, Eleonora .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2009, 54 (03) :180-187
[3]
Intracellular Ca2+ increases the mitochondrial NADH concentration during elevated work in intact cardiac muscle [J].
Brandes, R ;
Bers, DM .
CIRCULATION RESEARCH, 1997, 80 (01) :82-87
[4]
CA-2+ AS A 2ND MESSENGER WITHIN MITOCHONDRIA OF THE HEART AND OTHER TISSUES [J].
DENTON, RM ;
MCCORMACK, JG .
ANNUAL REVIEW OF PHYSIOLOGY, 1990, 52 :451-466
[5]
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation [J].
Erickson, Jeffrey R. ;
Joiner, Mei-ling A. ;
Guan, Xiaoqun ;
Kutschke, William ;
Yang, Jinying ;
Oddis, Carmine V. ;
Bartlett, Ryan K. ;
Lowe, John S. ;
O'Donnell, Susan E. ;
Aykin-Burns, Nukhet ;
Zimmerman, Matthew C. ;
Zimmerman, Kathy ;
Ham, Amy-Joan L. ;
Weiss, Robert M. ;
Spitz, Douglas R. ;
Shea, Madeline A. ;
Colbran, Roger J. ;
Mohler, Peter J. ;
Anderson, Mark E. .
CELL, 2008, 133 (03) :462-474
[6]
Elevated Cytosolic Na+ Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes [J].
Kohlhaas, Michael ;
Liu, Ting ;
Knopp, Andreas ;
Zeller, Tanja ;
Ong, Mei Fang ;
Boehm, Michael ;
O'Rourke, Brian ;
Maack, Christoph .
CIRCULATION, 2010, 121 (14) :1606-U54
[7]
Enhancing mitochondrial Ca2+ uptake in myocytes from failing hearts restores energy supply and demand matching [J].
Liu, Ting ;
O'Rourke, Brian .
CIRCULATION RESEARCH, 2008, 103 (03) :279-288
[8]
Role of mitochondrial dysfunction in cardiac glycoside toxicity [J].
Liu, Ting ;
Brown, David A. ;
O'Rourke, Brian .
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2010, 49 (05) :728-736
[9]
Oxygen free radical release in human failing myocardium is associated with increased activity of Rac1-GTPase and represents a target for statin treatment [J].
Maack, C ;
Kartes, T ;
Kilter, H ;
Schäfers, HJ ;
Nickenig, G ;
Böhm, M ;
Laufs, U .
CIRCULATION, 2003, 108 (13) :1567-1574
[10]
Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes [J].
Maack, Christoph ;
Cortassa, Sonia ;
Aon, Miguel A. ;
Ganesan, Anand N. ;
Liu, Ting ;
O'Rourke, Brian .
CIRCULATION RESEARCH, 2006, 99 (02) :172-182